Progress continues to happen in all areas of medicine. Don't worry at all about Vitamin K1 or either K2-MK7 or K2-MK4 while on Eliquis, Xeralto or the new Edoxaban just approved by the FDA as the third Factor Xa inhibitor NOAC. You can take as much Vitamin K as you might reasonably want for better health without any problems with these NOAC drugs. Known as a beta-adrenergic blocking agent, or beta blocker for short, metoprolol relaxes blood vessels and reduces your heart rate by interfering with processes involving epinephrine (also called adrenaline), according to the Mayo Clinic.By blocking some of epinephrine's effects, which include signaling the heart to pump faster, metoprolol helps the heart work more effectively for those with.